Vitamins usually don't cause swelling or joint pain. Because these symptoms seem to be related, it would be best to talk about vitamin intake with. In addition, a study that followed 37 patients with early-stage rheumatoid arthritis for one year revealed that those with low vitamin D levels at the start of the study did not respond as well to treatment and were less likely to achieve a remission than patients with normal levels of vitamin D. Some people have also used glucosamine to treat rheumatoid arthritis and other conditions, such as inflammatory bowel disease, asthma, allergies, chronic venous insufficiency, sports injuries, temporomandibular joint (TMJ) problems and long-term low back pain In the second RCT, 29 people with arthrosis in the hand were randomly assigned to receive 6,400 μg of vitamin B9, a combination of 6,400 μg of vitamin B9 and 20 μg of vitamin B12, or placebo tablets once a day for two months.
In combination with other treatments for osteoarthritis (as considered appropriate by the physician), taking glucosamine and chondroitin sulfate dietary supplements may help some patients achieve optimal levels of relief from joint pain related to osteoarthritis. With the exception of vitamin B12, which can be stored in the liver for up to four years, the body stores all water-soluble vitamins for only a short period of several weeks to several months and then eliminates them through the urine. In this trial‡, 43 participants with rheumatoid arthritis were randomly assigned to receive 5 mg of vitamin B9 with or without 100 mg of vitamin B6 once a day for 12 weeks.